Transcriptome analysis of isolated hyper-producer carotenoids mutants

Transcriptome analysis of isolated hyper-producer carotenoids mutants obtained via adaptive evolution. Transcriptome of isolated strains was compared with the ancestral strain as reference. To emulate evolution experiments, the cells were grown in YPD until late-exponential phase. Three biological replicas of 4 samples vs reference (sample SM12 contains 4 replicas). Location of the samples in the two microarrays are described below.通过适应性进化获得的类胡萝卜素（carotenoids）高产突变株的转录组分析。本研究以祖先菌株作为参照，对分离得到的突变株转录组进行对比分析。为模拟进化实验流程，将菌株接种于YPD培养基中培养至指数生长后期。针对4组对照样本，每组设置3个生物学重复；其中样本SM12包含4次生物学重复。样本在两张基因芯片（microarrays）上的排布位置详见下文。