The data of study about the chitosan-selenium nanoparticles on depression-like behaviour induced by fluoride in mice via JAK2-STAT3 pathway

These data demonstrated that 0.5 mg/kg·bw and 1 mg/kg·bw CS-SeNPs CS-SeNPs alleviated the depression-like behavior induced by the fluoride. The current data revealed that 0.5 mg/kg·bw and 1 mg/kg·bw CS-SeNPs significantly reduced the immobility time in TST and FST at 120 d rather than 60 d. These data provide a reference for nano-selenium as an antidepressant. These data can be used to make relevant comparisons and supplements for future antidepressant mechanism researchers.本实验数据证实，0.5 mg/kg·bw与1 mg/kg·bw的CS-SeNPs（Chitosan Selenium Nanoparticles）可缓解氟化物诱导的抑郁样行为。本次研究数据显示，0.5 mg/kg·bw与1 mg/kg·bw的CS-SeNPs可于造模后120天（而非60天）显著缩短悬尾实验（TST, Tail Suspension Test）与强迫游泳实验（FST, Forced Swim Test）中的不动时间。 本研究数据为纳米硒作为抗抑郁剂提供了参考依据。本研究数据可为未来抗抑郁机制相关研究人员开展相关对比与补充研究提供参考。