Respiratory and gut microbiome in CF patients. Nasopharyngeal, oropharyngeal, sputum, feces

Microbiome samples from the respiratory tract and gut in patients with CF with one S1251N mutation were obtained before and during use of ivacaftor to study microbial community composition changes.

本研究采集了携带一处S1251N突变的囊性纤维化（Cystic Fibrosis, CF）患者在使用依伐卡托 (ivacaftor) 前及用药期间的呼吸道与肠道微生物组 (Microbiome) 样本，旨在探究其微生物群落组成的变化。