SH1409068.10FU

UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.

UNITE数据库为基于DNA的物种假说（Species Hypotheses，以下简称SH）的界定、识别、交流与处理提供了统一的解决方案。国际核苷酸序列数据库中的全部真菌ITS序列，均通过应用一套动态距离取值区间（0.5%~3.0%）完成近似物种级别的聚类。所有物种假说均被赋予唯一且稳定的数字对象标识符（DOI）格式名称，其分类学与生态学注释信息将通过分布式的网络第三方注释工作完成验证。系统会结合每个物种假说聚类簇内所有序列的鉴定结果，尽可能将该假说关联至对应的分类单元名称及其分类层级（如门、纲、目等）。系统将选取一条自动指定或人工标定的序列，作为对应物种假说的代表序列。上述代表序列已对外发布（访问链接：https://unite.ut.ee/repository.php），可供科研群体用于本地序列相似性检索以及下一代测序（next-generation sequencing）分析流程等研究场景。随着公共真菌ITS序列库规模的持续增长，该系统及其配套数据将自动完成更新。