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Transcription profiling of human systemic lupus erythematosus patients to develop a transcriptional indicator of disease progression

ChEBI2008-10-01 更新2026-07-21 收录

系统性红斑狼疮

转录组生物标志物

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-11909 数据链接链接失效反馈

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资源简介：

Transcription profiling of human systemic lupus erythematosus patients to develop a transcriptional indicator of disease progression

应用场景：

创建时间：

2008-10-01

关节炎分子机制

转录组生物标志物

Meniscus plays an important role in joint homeostasis. Tear or degeneration of meniscus might facilitate the process of knee osteoarthritis (OA). Hence, to investigate the transcriptome change during

NIAID Data Ecosystem90

Table_3_Disease Activity-Associated Alteration of mRNA m5 C Methylation in CD4+ T Cells of Systemic Lupus Erythematosus.xlsx

系统性红斑狼疮

mRNAm5C甲基化分析

Epigenetic processes including RNA methylation, post-translational modifications, and non-coding RNA expression have been associated with the heritable risks of systemic lupus erythematosus (SLE). In

NIAID Data Ecosystem20

Table 6_Identification of circRNA expression signatures correlated with disease severity in pediatric systemic lupus erythematosus.xls

系统性红斑狼疮

circRNA生物标志物识别

BackgroundSystemic lupus erythematosus (SLE) is a complex systemic autoimmune disease with no current cure. Developing diagnostic biomarkers is crucial for improving patient outcomes. Circular RNAs (c

NIAID Data Ecosystem00

Evaluation of global methylation profile in recipient BMMSCs of MRL/lpr mice after cell therapy (MeDip). Mus musculus

表观遗传治疗

系统性红斑狼疮

Mesenchymal stem cell transplantation (MSCT) has been widely used to treat a variety of human diseases. However, the detailed mechanisms underlying its success are not fully understood. Here we show t

NIAID Data Ecosystem30

Groups of IgG N-glycans from Table 3 that showed statistically significant difference in observed values (corrected by sex, age, and African admixture) between 101 Afro-Caribbean cases with SLE and 183 controls.

肿瘤糖基化组学

系统性红斑狼疮

*t-test for equality of means (2-tailed).

NIAID Data Ecosystem20