Single cell data

Time-resolved analysis of nuclear-to-cytoplasmic SMAD2 ratio in individual cells. For some datasets, data regarding motility and cell death is included as well. Data is provided in CSV format and generally organized in time points (rows) and individual cells (columns). For each experiment, several files are provided: _data.csv - nuc/cyt SMAD2 ratio _conditions.csv - labeling of experimental conditions _map.csv - vector mapping individual cells to experimental conditions, numbering is according to the order given in the corresponding _conditions.csv file. _timeLine.csv - time points for measurements given in minutes _motility.csv - distance moved per time point given in µm/h _division.csv - number of divisions for each cells _fractiondead.csv - fraction of dead cells per field of view - please note that this data is not resolved at the single cell level! The MATLAB script "ReproduceFigures.m" allows to reproduce most data panels from the publication and should help to guide you through the data. Effect sizes need to be calculated separately using the function "permTest.m" and the parameters given in the publication.

单个细胞内核质SMAD2比值的时间分辨分析。部分数据集还涵盖了细胞运动性与细胞死亡相关数据。数据集以CSV格式存储，整体按照时间点（行）与单个细胞（列）的结构进行组织。针对每项实验，提供了以下多个文件：
_data.csv：核/质SMAD2比值数据
_conditions.csv：实验条件标注文件
_map.csv：将单个细胞映射至实验条件的向量文件，细胞编号与对应_conditions.csv文件中的顺序一致
_timeLine.csv：以分钟为单位的测量时间点文件
_motility.csv：以µm/h为单位的各时间点移动距离文件
_division.csv：各细胞的分裂次数文件
_fractiondead.csv：各视野的死细胞占比文件——请注意该数据未在单细胞分辨率下解析
MATLAB脚本"ReproduceFigures.m"可复现该论文中的绝大多数数据图表，能够辅助使用者熟悉并使用该数据集。效应量需通过"permTest.m"函数结合论文中给出的参数单独计算。