CA-3Y

CA-3Y investigates the impact of Lactobacillus <i>acidophilus</i> treatment on the gut microbiota in Clostridioides difficile infection. Fecal samples from mice post-infection were processed using Invitrogen with sequencing on the Ion Torrent NGS System. Analysis via Ion Reporter SW (16S) revealed shifts in microbial taxa dynamics over days 1, 3, and 6, shedding light on the potential of probiotics in modulating gut microbiota during C. difficile infection.The identification of the sample CA-3Y:<br>C: Denotes the strain ST-4 of Clostridioides difficile.<br>A: Represents timepoint 1, indicating sampling before C. difficile infection.<br>3: Refers to the specific mouse number under investigation.<br>Y: Indicates the treatment administered, which in this case is Lactobacillus <i>acidophilus</i>.

CA-3Y数据集旨在探究嗜酸乳杆菌（Lactobacillus acidophilus）干预对艰难梭菌（Clostridioides difficile）感染小鼠肠道菌群的影响。感染后小鼠的粪便样本采用英维创（Invitrogen）相关试剂进行前处理，并通过Ion Torrent二代测序（NGS）系统完成测序。借助Ion Reporter SW（16S）分析工具，研究人员观测到感染后第1、3、6天的微生物类群动态变化，为阐明益生菌在艰难梭菌感染期间调控肠道菌群的潜在价值提供了依据。
样本CA-3Y的命名规则如下：
C：代表所使用的艰难梭菌菌株ST-4；
A：表示采样时间点为艰难梭菌感染前；
3：指代本次研究的特定小鼠编号；
Y：代表施加的干预措施为嗜酸乳杆菌（Lactobacillus acidophilus）。