The genomic ancestry, landscape genetics, and invasion history of introduced mice in New Zealand

The house mouse (Mus musculus) provides a fascinating system for studying both the genomic basis of reproductive isolation, and the patterns of human- mediated dispersal. New Zealand has a complex history of mouse invasions, and the living descendants of these invaders have genetic ancestry from all three subspecies, although most are primarily descended from M. m. domesticus. We used the GigaMUGA genotyping array (~135,000 loci) to describe the genomic ancestry of 161 mice, sampled from 34 locations from across New Zealand (and one Australian city - Sydney). Of these, two populations, one in the south of the South Island, and one on Chatham Island, showed complete mitochondrial lineage capture, featuring two different lineages of M. m. castaneus mitochondrial DNA but with only M. m. domesticus nuclear ancestry detectable. Mice in the northern and southern parts of the North Island had small traces (~2-3%) of M. m. castaneus nuclear ancestry, and mice in the upper South Island had ~7...

小家鼠（Mus musculus）是研究生殖隔离的基因组基础以及人类介导的扩散模式的极具价值的实验体系。新西兰拥有复杂的小家鼠入侵历史，这些入侵种群的现存后代携带三个小家鼠亚种的遗传血统，尽管多数个体主要源自小家鼠家栖亚种（M. m. domesticus）。本研究采用GigaMUGA基因分型芯片（约135,000个位点）对161只小家鼠开展基因组血统分析，样本采集自新西兰全境34个采样点以及澳大利亚城市悉尼。其中两个种群——分别位于南岛南部与查塔姆群岛——呈现完全的线粒体谱系捕获现象：它们携带两种不同的小家鼠东南亚亚种（M. m. castaneus）线粒体DNA谱系，但仅能检测到家栖亚种的核血统。北岛北部与南部的小家鼠仅带有少量（约2%-3%）东南亚亚种的核血统，而南岛北部的小家鼠则拥有约7%……