f6d310eb-68f1-461d-b3f6-4620d698e827 - samples

The dataset consists of Oxford Nanopore targeted RNA-based amplicon data of 12 classical HLA genes (HLA-A, -B, -C, -DRA, -DRB1, -DRB3, -DRB4, -DRB5, -DQA1, -DQB1, -DPA1, and DPB1) of 50 healthy individuals. The 12 classical genes were sequenced in two separate gene pools on R9.4 flowcells using MinION sequencer. Per individual, gene pool 1 contains HLA-A, -B, -C, -DRB1, -DRB3, -DRB4, -DRB5, and -DPB1 and gene pool 2 HLA-DRA, -DQA1, -DQB1, and -DPA1. The dataset includes 100 fastq files of Oxford Nanopore 2D reads (50 for gene pool 1 and 50 for gene pool 2).EGA dataset EGAD00001006814

本数据集涵盖50名健康个体的12种经典人类白细胞抗原（HLA, Human Leukocyte Antigen）基因的牛津纳米孔（Oxford Nanopore）靶向RNA扩增子测序数据，涉及基因包括HLA-A、-B、-C、-DRA、-DRB1、-DRB3、-DRB4、-DRB5、-DQA1、-DQB1、-DPA1及DPB1。研究团队使用MinION测序仪，在R9.4流动槽（R9.4 flowcells）上将这12个经典HLA基因分为两个独立的基因池完成测序。针对每名个体，基因池1包含HLA-A、-B、-C、-DRB1、-DRB3、-DRB4、-DRB5及DPB1，基因池2则包含HLA-DRA、-DQA1、-DQB1及-DPA1。本数据集包含100份牛津纳米孔2D测序读段的fastq文件，其中基因池1与基因池2各50份。该数据集的欧洲基因组学档案（EGA, European Genome-phenome Archive）编号为EGAD00001006814。