遇见数据集

Additional file 1: of DNA methylation signature is prognostic of choroid plexus tumor aggressiveness

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Table S1. Patient information for samples used in DNA methylation experiment. Table S2. Patient information for samples in replication cohort used in sensitivity testing of the CPC DNA methylation signature. Table S3. Multivariate factor analysis. Table S4. Primer sets for quantitative sodium bisulfite pyrosequencing. Table S5. GABA receptor DNA methylation status in CPTs. Table S6. Differentially methylated genes in cpc vs cpp showing differential expression and reverse correlation with DNA methylation in the promoter region of the gene. Table S7. Differentially methylated genes in cpc vs cpp showing differential expression and positive correlation with DNA methylation in the body of the gene. Table S8. 39 variables (encompassing 33 single genes) segregating CPCs and CPPs. Table S9. Comparison between CPC-specific DNAm signature classification and the Heidelberg classifier. (XLSX 108 kb)

表S1:DNA甲基化(DNA methylation)实验所用样本的患者信息。 表S2:用于CPC的DNA甲基化特征敏感性检测的重复队列样本的患者信息。 表S3:多因素因子分析。 表S4:定量亚硫酸氢盐焦磷酸测序(quantitative sodium bisulfite pyrosequencing)引物组。 表S5:CPTs中GABA受体的DNA甲基化状态。 表S6:CPC与CPP之间的差异甲基化基因,此类基因既存在差异表达,且与基因启动子区域的DNA甲基化呈负相关。 表S7:CPC与CPP之间的差异甲基化基因,此类基因既存在差异表达,且与基因体区域的DNA甲基化呈正相关。 表S8:用于区分CPC与CPP的39个变量(涵盖33个单基因)。 表S9:CPC特异性DNA甲基化特征分类与海德堡分类器的比较(XLSX 108 kb)

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2019-08-13
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