Additional file 1 of Analysis of transcriptomic features reveals molecular endotypes of SLE with clinical implications
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Additional file 1: This additional file consists of the following supplementary tables referenced throughout the manuscript: Table S1. Summary of transcriptional whole blood lupus datasets. Table S2. Comparison of clustering algorithms in GSE88884 ILL-1 & ILL-2. Table S3. GSVA enrichment scores and endotype membership of SLE patients. Table S4. Binary classifier performance metrics for eight lupus endotypes. Table S5. Contingency tables for severe flare calculation in placebo patients from GSE88884 ILL-1 & ILL-2. Table S6. Characteristics of clinically responsive endotypes to tabalumab in GSE88884 ILL-2. Table S7. Contingency tables for severe flare calculation in placebo patients from GSE88884 ILL-2.
附加文件1:本附加文件包含手稿全文引用的如下补充表格:
表S1 全血狼疮转录组数据集汇总
表S2 GSE88884队列ILL-1与ILL-2中聚类算法的对比分析
表S3 系统性红斑狼疮(Systemic Lupus Erythematosus, SLE)患者的基因集变异分析(Gene Set Variation Analysis, GSVA)富集得分及内型(endotype)归属
表S4 8种狼疮内型的二分类分类器性能指标
表S5 GSE88884队列ILL-1与ILL-2中安慰剂组患者重度病情加重计算的列联表
表S6 GSE88884队列ILL-2中对他利单抗(tabalumab)存在临床应答的狼疮内型的特征
表S7 GSE88884队列ILL-2中安慰剂组患者重度病情加重计算的列联表
提供机构:
figshare
创建时间:
2023-10-17



