Baseline association between Health Eating Index 2015 and health-related quality of life in breast cancer survivors enrolled in a randomized trial

Quality of life significantly affects health outcomes in cancer patients. However, evidence on the association between diet quality and quality of life in cancer survivors is sparse. The aim of this study was to evaluate the associations between an a priori diet quality index, the Healthy Eating Index 2015 (HEI-2015) and quality of life, assessed through a validated questionnaire in women with a breast cancer diagnosis. Higher HEI-2015 score was positively associated with summary quality of life score, with functional scale and inversely associated with symptoms scale. Significant associations were also found between single HEI-components and overall quality of life scores. These results suggest that higher quality of diet could positively affect quality of life of breast cancer survivors living in a Mediterranean country, highlighting the need to implement nutritional treatment in breast cancer survivors as part of a multidisciplinary approach to improve quality of life and related health outcomes.

生活质量对癌症患者的健康结局具有显著影响。然而目前针对癌症幸存者饮食质量与生活质量之间关联的研究证据仍较为匮乏。本研究旨在通过经信效度验证的问卷，评估乳腺癌确诊女性群体中，先验饮食质量指数——2015年健康饮食指数（Healthy Eating Index 2015, HEI-2015）与生活质量的关联。研究结果显示，较高的HEI-2015评分与总体生活质量评分、功能量表得分呈正相关，而与症状量表得分呈负相关。此外，HEI-2015的单个组成维度与总体生活质量评分之间也存在显著关联。本研究结果表明，对于居住在地中海国家的乳腺癌幸存者而言，更高的饮食质量可对其生活质量产生积极影响；这一发现凸显了将营养干预纳入乳腺癌幸存者照护的必要性，将其作为多学科诊疗模式的一部分，以改善患者的生活质量及其相关健康结局。