Structure of Focal Adhesion Kinase catalytic domain in complex with novel allosteric inhibitor

Structure of Focal Adhesion Kinase catalytic domain in complex with novel allosteric inhibitor Descriptor: 8-(4-ethylphenyl)-5-methyl-2,5-dihydropyrazolo[4,3-c][2,1]benzothiazine 4,4-dioxide, Focal adhesion kinase 1, ISOPROPYL ALCOHOL Authors: Skene, R.J, Hosfield, D.J. Deposit date: 2012-03-25 Release date: 2012-08-22 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.67 Å) Cite: Discovery and characterization of novel allosteric FAK inhibitors. Eur.J.Med.Chem., 61, 2013与新型变构抑制剂结合的黏着斑激酶（Focal Adhesion Kinase, FAK）催化域结构 配体描述：8-(4-乙基苯基)-5-甲基-2,5-二氢吡唑并[4,3-c][2,1]苯并噻嗪4,4-二氧化物、黏着斑激酶1、异丙醇 作者：Skene, R.J.、Hosfield, D.J. 存档日期：2012-03-25 发布日期：2012-08-22 最后修改日期：2024-10-09 实验方法：X射线衍射（分辨率1.67 Å） 引用文献：新型变构FAK抑制剂的发现与表征. Eur.J.Med.Chem., 61, 2013