Supplemental Table 3. Exome-wide MTR scores.

Supplementary Table 3: Exome-wide MTR scores. Expected and observed counts of missense and synonymous variants observed in each 31-codon window centered on possible missense variants exome-wide using data from 824K unrelated individuals. MTR values for all missense variants and p-value from binomial test, and FDR corrected q-value. MTRPercentileExome and MTRPercentileTranscript represent the percentile of MTR score across the exome and within a transcript, respectively.

补充表3：全外显子组MTR评分（Exome-wide MTR scores）。本研究基于82.4万名无关个体的测序数据，对全外显子组范围内每一个以潜在错义变异为中心的31密码子窗口中的错义变异与同义变异，统计其预期与实际观测计数。表格涵盖所有错义变异的MTR值、二项检验得到的P值，以及经错误发现率（False Discovery Rate, FDR）校正的q值。其中，MTR全外显子组百分位（MTRPercentileExome）与MTR转录本百分位（MTRPercentileTranscript）分别代表全外显子组全域及单个转录本内MTR评分的百分位数。