Genomic insights into the dynamics of antimicrobial resistance in clinical isolates of Vibrio spp. collected over 16 year period in India

The prevalence of antimicrobial resistance (AMR) in Vibrio cholerae is both dynamic and rapidly evolving, highlighting the importance of understanding and addressing the challenges it presents. This study examines the diversity of clinical Vibrio cholerae isolates in India collected over 16 years (2008 to 2023) and assesses the impact of gene flux in a cholera-endemic region.

霍乱弧菌（Vibrio cholerae）的抗菌素耐药性（antimicrobial resistance, AMR）呈现动态变化且快速演化的态势，凸显了认知并应对其带来的挑战的重要性。本研究针对2008年至2023年这16年间在印度采集的临床分离霍乱弧菌菌株的多样性开展分析，并评估了基因流（gene flux）在霍乱流行区所产生的影响。