A small fraction of S. Typhimurium is tolerant to conditions that mimic stressors associated with infection.
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Bacteria were grown to late log phase in LB and exposed to antibiotics (A) ampicillin, 100 μg/mL, (B) ciprofloxacin, 0.2 μg/mL, (C) polymyxin B, 5 μg/mL, (D) hydrogen peroxide, 1.25 mM, (E) pH 2.6–4.4, or (F) dipyridyl, 0–30 mM. Bacteria were monitored thereafter for survival by plating to LB-agar plates and enumerating CFU. Mean of > 4 independent experiments are shown; error bars denote SEM.
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2016-02-22



