Supplementary File 1 of manuscript entitled Unveiling the Anticancer Potential of Mangroves: A 2005−2024 Bibliometric Analysis

Context: Demographic forecasts indicate that new cancer cases may reach 35 million by 2050, intensifying the need for novel, regionally tailored control strategies. Mangroves have yielded multiple potential anticancer compounds in recent years, but no bibliometric investigation of their role has been performed. This study aimed to provide a bibliometric overview of research on anticancer activity from mangroves.Methods: We used keywords related to anticancer activity and mangroves to search the Scopus database. VOSviewer and Biblioshiny were used for further analysis.Results: We identified 87 studies on cancer-associated mangroves, with an annual growth rate of 9.89%. Publications have increased since 2005, peaking in 2020. The top five countries and organizations in productivity were China, India, Indonesia, Malaysia, and Thailand. The top five affiliations were Guangdong Medical University, Shanghai Jiao Tong University, Sun Yat-Sen University, Wuhan University, and Guangdong University of Technology. Wu X, Liu J, Basyuni M, and Tang X were the most prolific authors. Five primary study themes emerged: antineoplastic activity, mangroves, apoptosis, cell proliferation, and protein expression.背景：人口统计学预测显示，到2050年全球新增癌症病例或将达到3500万例，这进一步强化了对新型、因地制宜的癌症防控策略的迫切需求。近年来，红树林已被发现多种具有抗癌潜力的天然化合物，但目前尚无针对其抗癌作用的文献计量学（bibliometric）研究。本研究旨在对红树林来源的抗癌活性相关研究开展文献计量学综述。 方法：本研究使用与抗癌活性及红树林相关的关键词检索Scopus数据库，并采用VOSviewer与Biblioshiny工具进行后续分析。 结果：本研究共筛选得到87篇与癌症相关的红树林研究文献，年均增长率达9.89%。自2005年起，相关文献发表量持续攀升，并于2020年达到峰值。发文量排名前五的国家与地区依次为中国、印度、印度尼西亚、马来西亚与泰国；前五家研究机构分别为广东医科大学、上海交通大学、中山大学、武汉大学及广东工业大学。吴X、刘J、Basyuni M以及唐X为该领域的高产作者。本研究归纳出五大核心研究主题：抗肿瘤活性、红树林、细胞凋亡、细胞增殖及蛋白质表达。