Supplementary data 3. The gene regulatory interactions involving NAFLD-candidate genes within the LGRN, and the trait enrichment results of the regulatory eQTLs targeting those genes.
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https://auckland.figshare.com/articles/dataset/Supplementary_data_3_The_gene_regulatory_interactions_involving_NAFLD-candidate_genes_within_the_LGRN_and_the_trait_enrichment_results_of_the_regulatory_eQTLs_targeting_those_genes_/17087114/1
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The spatially constrained eQTLs associated with the differential regulation of the NAFLD-candidate genes were identified from the LGRN. There were 122 spatially constrained eQTLs regulating 13 NAFLD-candidate genes. And the eQTLs were significantly enriched for the GWAS traits linked with NAFLD such as liver enzyme levels.
通过对LGRN中与NAFLD候选基因差异调控相关的空间限制性eQTLs进行分析,共识别出122个调控13个NAFLD候选基因的空间限制性eQTLs。这些eQTLs在NAFLD相关GWAS性状(如肝脏酶水平)中显著富集。
提供机构:
The University of Auckland



