RNAseq analysis of SARS-CoV-2 infection of A549ACE cells

Analysis of histone mimicry by SARS-CoV-2 Orf8 encoded protein SARS-CoV-2 WT virus, Orf8 deletion virus, or mock infection of A549-ACE cells was performed and RNA was collected at 24 or 48 hours after infection本研究针对新型冠状病毒（SARS-CoV-2）Orf8编码蛋白介导的组蛋白模拟（histone mimicry）现象展开分析，分别采用野生型SARS-CoV-2病毒、Orf8缺失型病毒感染A549-ACE细胞，并设置假感染（mock infection）对照组，于感染后24小时或48小时收集RNA样本。