MEF2C chip in the skeletal muscle of PRR14-KO mice

the expression and splice forms are regulated in the skeletal muscle of PRR14-KO mice, to explore the underlying mechanism of MEF2C-mediated PRR14's function in skeletal muscle, the chip assay was performed MEF2C chip assay was performed in the skeletal muscle of PRR14-KO mice and PRR14-WT mice.PRR14基因敲除（PRR14-KO）小鼠的骨骼肌中，基因的表达与剪接形式均受到调控。为探究肌细胞增强因子2C（Myocyte Enhancer Factor 2C, MEF2C）介导PRR14在骨骼肌中发挥功能的潜在分子机制，本研究在PRR14基因敲除（PRR14-KO）与野生型（PRR14-WT）小鼠的骨骼肌中开展了MEF2C染色质免疫沉淀（Chromatin Immunoprecipitation, ChIP）实验。