Adjusted coefficients examining direct effects of prepubertal risk factors on age at breast development onset (TS II); direct effects of prepubertal risk factors and age at breast development onset (TS II) on the adulthood CMR composite; and mediated effects of prepubertal risk factors on the adulthood CMR composite via age at breast development onset (TS II).

Adjusted coefficients examining direct effects of prepubertal risk factors on age at breast development onset (TS II); direct effects of prepubertal risk factors and age at breast development onset (TS II) on the adulthood CMR composite; and mediated effects of prepubertal risk factors on the adulthood CMR composite via age at breast development onset (TS II).

本数据集的经校正系数用于分析以下三类效应：一是青春期前危险因素对乳房发育启动年龄（TS II）的直接效应；二是青春期前危险因素与乳房发育启动年龄（TS II）对成年期心血管代谢风险（Cardiometabolic Risk, CMR）综合指标的直接效应；三是青春期前危险因素通过乳房发育启动年龄（TS II）介导对成年期CMR综合指标产生的介导效应。