PRL2013 gene expression on Caco-2/HT29-MTX monolayers

To explore the genetic mechanisms involved in the B. animalis subsp. lactis PRL2013 interaction with the human host, a transcriptomic analysis was performed on Caco-2/HT29-MTX cell monolayers exposed to PRL2013 cells. Following, shotgun transcriptomics was carried out to investigate PRL2013 gene expression stimulated by human cells contact.为探究动物双歧杆菌乳亚种（B. animalis subsp. lactis）PRL2013与人类宿主的互作遗传机制，本研究对暴露于PRL2013菌体的Caco-2/HT29-MTX细胞单层开展了转录组分析。继而，通过鸟枪法转录组学，对人类细胞接触诱导的PRL2013基因表达进行了研究。