Ipsilateral brain injuries observed histologically from individual aging mice.

Ipsilateral brain injury was recognized through hypochromic staining when examined at 24–48 hours post-HI or cystic infarctions at 4–5 weeks post HI. Column 1: Animal ID of each aging mouse examined. Columns 2–6: injured brain structures indicated by ‘+’. Abbreviations: HIPP—hippocampus; LAT CORT—lateral cortex; STR—striatum; TH—thalamus; MB/BST—midbrain and brainstem areas. Column 7: ipsilateral regions with hypochromic staining where clearly recognized boundaries were present and quantifiable in 6 animals. These regions were measured at 8 coronal levels (bregma 1.9, 1.2, 0.5, -0.2, -1.1, -1.5, -2.4 and -3.2 mm respectively) and normalized as a % of total ipsilateral hemispheric area. The mean±SE from multiple coronal levels were presented for each animal. Column 8: ipsilateral brain injury observed for other animals in which injury margins were difficult to demarcate. For these animals, the coronal levels at which hypochromic staining or infarctions were observed were indicated for each animal instead.Ipsilateral brain injuries observed histologically from individual aging mice.本数据集可通过缺氧缺血（HI）造模后24~48小时取材时的淡染染色（hypochromic staining），或造模后4~5周时的囊性梗死灶，识别受试动物的损伤侧大脑损伤。 第1列：每只受试老龄小鼠的动物标识号（Animal ID）。 第2~6列：以“+”标记的受损脑区。 缩写说明：HIPP—海马体（hippocampus）；LAT CORT—外侧皮层（lateral cortex）；STR—纹状体（striatum）；TH—丘脑（thalamus）；MB/BST—中脑与脑干区域（midbrain and brainstem areas）。 第7列：6只受试动物中边界清晰可辨、可量化的淡染染色（hypochromic staining）损伤侧脑区。该类脑区通过8个冠状层面（分别对应前囟点（bregma）1.9、1.2、0.5、-0.2、-1.1、-1.5、-2.4及-3.2 mm）进行测量，并以占损伤侧大脑半球总面积的百分比进行归一化处理。每只动物的结果均为多冠状层面的均值±标准误（SE）。 第8列：其余难以划定损伤边界的受试动物的损伤侧脑损伤情况。针对此类动物，本数据集转而标注其观察到淡染染色或梗死灶的冠状层面。 本数据集为单只老龄小鼠经组织学检测得到的损伤侧脑损伤数据。