The local cellular response to Human Papillomavirus focuses on basal layer restoration as visualized in situ by specific cellular neighborhoods near infected cells

We applied spatial single-cell spatial transcriptomics to formalin-fixed paraffin-embedded healthy vulvar tissue (n=5) and HPV16+ high grade vulvar lesions (vHSIL, n=31).我们将空间单细胞空间转录组学（spatial single-cell spatial transcriptomics）技术应用于福尔马林固定石蜡包埋的健康外阴组织（n=5）及HPV16阳性高级别外阴病变（vHSIL，n=31）。