Figure S1 - Pfit Is a Structurally Novel Crohn's Disease-Associated Superantigen

Sequence alignment of pfiT with representative TetR-family members. (A) Sequence alignment of pfiT with representative putative TetR members within Pseudomonas families. Residues are colored according to the extent of their sequence conservation: >90% conserved (red); 50–90% conservation (blue); less or not conserved (B) Sequence alignment of pfiT with representative putative TetR members of other bacterial species. Abbreviations used here include: P., Pseudomonas; H., Hahella; B., Bermanella; M., Marinobacter; Al., Alcanivorax; A., Acinetobacter; G., Glaciecola; Ps., Pseudogulbenkiania; Ma., Marinithermus. (DOCX)pfiT与代表性TetR家族（TetR-family）成员的序列比对分析。（A）pfiT与假单胞菌类群内代表性推定TetR家族成员的序列比对分析。残基根据其序列保守程度着色：保守度＞90%（红色）；保守度50%~90%（蓝色）；保守度较低或无保守性（（B）pfiT与其他细菌物种代表性推定TetR家族成员的序列比对分析。本文所用缩写如下：P. 代表假单胞菌属（Pseudomonas）；H. 代表哈氏菌属（Hahella）；B. 代表伯曼氏菌属（Bermanella）；M. 代表海杆菌属（Marinobacter）；Al. 代表食烷菌属（Alcanivorax）；A. 代表不动杆菌属（Acinetobacter）；G. 代表冰河杆菌属（Glaciecola）；Ps. 代表假古尔班凯氏菌属（Pseudogulbenkiania）；Ma. 代表海热菌属（Marinithermus）。（DOCX）