o2n-seq. Sinsheimervirus phiX174

NIAID Data Ecosystem2026-03-09 收录

低频突变检测

病毒测序方法

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA339671 数据链接链接失效反馈

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资源简介：

A method for ultra-sensitive, high efficiency screen of de novo low-frequency mutation

一种用于超灵敏、高效筛选新发低频突变（de novo low-frequency mutation）的方法

创建时间：

2016-08-22

Data from: Benefits and challenges with applying unique molecular identifiers in next generation sequencing to detect low frequency mutations

基因测序

低频突变检测

Indexing individual template molecules with a unique identifier (UID) before PCR and deep sequencing is promising for detecting low frequency mutations, as true mutations could be distinguished from P

DataONE2016-01-22 更新100

Bisulfite-converted duplexes for the strand-specific detection and quantification of rare mutations

低频突变检测

精准医学测序

The identification of mutations that are present at low frequencies in clinical samples is an essential component of precision medicine. The development of molecular barcoding for next generation sequ

NIAID Data Ecosystem60

MIPP-Seq: Ultra-sensitive rapid detection and validation of low-frequency mosaic mutations

低频突变检测

遗传病诊断

MIPP-Seq provides an ultra-sensitive, low-cost approach for detecting and validating known and novel mutations in a highly scalable system with broad utility spanning both research and clinical diagno

NIAID Data Ecosystem50

Enhanced Duplex Sequencing methodology for high efficiency error suppression at variable sequencing depths

癌症基因组数据

低频突变检测

Detection of cancer-associated somatic mutations has broad applications for oncology and precision medicine. However, this becomes challenging when DNA from cancer cells is in low abundance such as in

NIAID Data Ecosystem60

Influence of sequencing depth on the fidelity and sensitivity of 1%-5% low-frequency mutation detection

低频突变检测

测序深度优化

Influence of sequencing depth on the fidelity and sensitivity of 1%-5% low-frequency mutation detection and recommendations for standardization of sequencing depth calculation

DataCite Commons2021-12-27 更新60

o2n-seq. Sinsheimervirus phiX174

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