Temporal evaluation of human B cell-derived monoclonal antibodies against DENV.
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To generate the monoclonal antibodies (mAbs) listed in this table, peripheral blood mononuclear cells (PBMCs) had been taken after primary (1st) and secondary (2nd) infection or between the acute and convalescent phases. Note to table: in reports in which multiple donors had been used, all percentages were first calculated as % per donor and then averaged over all donors. Hence, some percentages in this table can differ from those in the reports in which the value is reported as the % of experiment rather than per donor. Not all antibodies were characterized; hence, values may be lower than 100%. n.d.: not determined. EDI/DII and DIII refer to the structural domains within the E ectodomain. Temporal evaluation of human B cell-derived monoclonal antibodies against DENV.
为制备本表格所列的单克隆抗体(monoclonal antibodies, mAbs),研究者采集了初次(第1次)与二次(第2次)感染后,或处于急性期与恢复期之间的外周血单个核细胞(peripheral blood mononuclear cells, PBMCs)。 表格说明:在使用多名供者的研究中,所有百分比均先按每位供者的百分比计算,再对所有供者取平均值。因此,本表格中的部分百分比可能与研究原文中以实验整体百分比而非供者均值报告的数值存在差异。并非所有抗体均完成表征,故部分数值可能低于100%。n.d.:未检测(not determined)。EDI/DII与DIII指代E蛋白胞外域内的结构域。 针对登革病毒(DENV)的人源B细胞单克隆抗体时序评估




