RNA Seq BCAS CRex

An animal model of vascular dementia caused by cerebral ischemia was created by reducing blood flow in the bilateral carotid arteries of mice, and the symptoms were confirmed to be improved by administering CRex, an herbal extract. Mouse brain tissue was extracted and major genes and proteins were analyzed through RNA Seq analysis.

本研究通过降低小鼠双侧颈动脉血流量，构建了脑缺血所致血管性痴呆的动物模型，并证实给予草本提取物CRex后，模型动物的症状得到改善。随后提取小鼠脑组织，通过RNA测序（RNA Seq）分析对其中的主要基因与蛋白质进行了检测分析。