Echocardiographic reference ranges for sedated healthy peccaries ( Tayassu tajacu, Linnaeus , 1758 )

ABSTRACT Peccaries are wild mammals belonging to the Tayassu genus that are found almost everywhere in the Americas and have demonstrated great potential as an experimental model for scientific investigations. Twelve healthy adult animals were sedated to perform echocardiographic examinations in B, M and Doppler mode. The variables that exhibited statistically significant correlation coefficients with weight were LVFWd, LVIDd, LVIDs, E wave, A’RV, MAM, and TAPSE. The HR exhibited a negative relationship with the IVRT. The LA variable showed a positive correlation with the AO. The MAM exhibited correlations with the LVIDd and LVIDs. The TAPSE showed positive correlations with the E’RV and A’RV. The present study provides the first reference values for echocardiographic measurements in B, M and Doppler modes from peccaries anesthetized with ketamine and midazolam. Echocardiography was easy to perform in collared peccaries, and the collected data revealed values that can aid in their clinical management and conservation.

摘要 西猯是隶属于西猯属（Tayassu）的野生哺乳类动物，广泛分布于美洲大陆各地，且已被证实为科学研究中极具潜力的实验动物模型。本研究选取12只健康成年西猯，予以镇静后采用B型、M型及多普勒模式开展超声心动图检查。与体重呈现统计学显著相关系数的变量包括左心室后壁舒张末期厚度（LVFWd）、左心室舒张末期内径（LVIDd）、左心室收缩末期内径（LVIDs）、E波、右心室A’峰（A’RV）、二尖瓣环运动幅度（MAM）及三尖瓣环收缩期位移（TAPSE）。心率（HR）与左心室等容舒张时间（IVRT）呈负相关关系。左心房内径（LA）与主动脉根部内径（AO）呈正相关。二尖瓣环运动幅度（MAM）与左心室舒张末期内径（LVIDd）及收缩末期内径（LVIDs）存在相关性。三尖瓣环收缩期位移（TAPSE）与右心室E’峰（E’RV）及A’峰（A’RV）呈正相关。本研究首次给出了使用氯胺酮与咪达唑仑麻醉的西猯采用B型、M型及多普勒模式进行超声心动图测量的参考值范围。在领西猯中开展超声心动图检查操作简便，本研究获取的数据可为其临床诊疗与物种保护提供参考依据。