anti-anxiety-memory-test

ContextAn experiment on the effects of anti-anxiety medicine on memory recall when being primed with happy or sad memories. The participants were done on novel Islanders whom mimic real-life humans in response to external factors.Drugs of interest (known-as) [Dosage 1, 2, 3]:A - Alprazolam (Xanax, Long-term) [1mg/3mg/5mg]T - Triazolam (Halcion, Short-term) [0.25mg/0.5mg/0.75mg]S- Sugar Tablet (Placebo) [1 tab/2tabs/3tabs]*Dosages follow a 1:1 ratio to ensure validity *Happy or Sad memories were primed 10 minutes prior to testing *Participants tested every day for 1 week to mimic addictionBuilding the Case: Obstructive effects of Benzodiazepines (Anti-Anxiety Medicine):Long term adverse effects on Long Term Potentiation of synapses, metacognition and memory recall ability http://www.jstor.org/stable/43854146Happy Memories:research shown positive memories to have a deeper and greater volume of striatum representation under an fMRI https://www.sciencedirect.com/science/article/pii/S0896627314008484Sad Memories:research shown sad memories invokes better memory recall for evolutionary purpose whereas, happy memories are more susceptible to false memories http://www.jstor.org/stable/40064315Participants - all genders above 25+ years old to ensure a fully developed pre-frontal cortex, a region responsible for higher level cognition and memory recall.ContentFile contains information on participants drug treatment information along with their test scores.AcknowledgementsExperiment was executed under the supervision of Mr. Almohalwas at UCLA. All aspects of the experiment such as experimental design, data collection and preprocessing was done from myself.InspirationHow does anti-anxiety medicine affect you differently by age? Is there a level of plateauing in effectiveness of anti-anxiety medicine - if so, at what point? Effect of anti-anxiety medicine on memory recall? Effectiveness of placebos in a test environment?实验背景：本实验旨在探究抗焦虑药物在受试者被启动快乐或悲伤记忆时，对其记忆提取能力的影响。实验对象为模拟现实人类对外界因素响应模式的新型岛民受试者。 目标受试药物（俗称）： A：阿普唑仑（Alprazolam，商品名赞安诺（Xanax），长效型）[1mg/3mg/5mg] T：三唑仑（Triazolam，商品名海乐神（Halcion），短效型）[0.25mg/0.5mg/0.75mg] S：糖丸（安慰剂）[1片/2片/3片] *所有受试药物剂量均遵循1:1:1配比，以保障实验效度* *于测试前10分钟启动受试者的快乐或悲伤记忆；参与者需连续7天每日接受测试，以模拟成瘾状态* 实验依据：苯二氮䓬类（Benzodiazepines，抗焦虑药物）的阻滞效应——长期使用该类药物会对突触长时程增强（Long Term Potentiation）、元认知（metacognition）及记忆提取能力产生不良影响，相关研究链接：http://www.jstor.org/stable/43854146 快乐记忆相关研究：已有研究表明，在功能磁共振成像（fMRI）下，积极记忆对应的纹状体表征更深且体积更大，相关研究链接：https://www.sciencedirect.com/science/article/pii/S0896627314008484 悲伤记忆相关研究：研究显示，从进化角度而言，悲伤记忆可引发更优的记忆提取效果；而快乐记忆则更易产生错误记忆，相关研究链接：http://www.jstor.org/stable/40064315 受试者筛选标准：所有参与者均为25岁及以上的各性别群体，以确保其前额叶皮层（pre-frontal cortex）发育完全——该区域负责高级认知与记忆提取功能。 数据文件说明：本文件包含受试者的药物治疗信息及对应的测试得分。 致谢：本实验由加州大学洛杉矶分校（UCLA）的Almohalwas先生指导完成，实验设计、数据收集与预处理等所有环节均由本人独立完成。 研究启发：抗焦虑药物如何因年龄不同而对个体产生差异化影响？抗焦虑药物的有效性是否存在平台期？若存在，其拐点位于何处？抗焦虑药物对记忆提取的影响如何？安慰剂在实验环境中的有效性如何？