CTRPv2
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CTRPv2 PharmacoSet (PSet) generated by ORCESTRA. Metadata can be found on ORCESTRA at: http://orcestra.ca/10.5281/zenodo.4429239 Disclaimer The CTRPv2 data were generated by the Broad Institute CTD^2 Center and originally released via the Cancer Therapeutics Response Portal (CTRP). The Haibe-Kains Lab has reprocessed and re-annotated the data to maximize overlap with other pharmacogenomic datasets. Data Usage Policy The CTD^2 releases data in accordance with their data release policy. The DepMap data, including the CTRPv2 data, are provided under Creative Commons Attribution 4.0 license. Contact depmap@broadinstitute.org for more information. Please cite the following when using these data Seashore-Ludlow B, Rees MG, Cheah JH, Cokol M, Price EV, Coletti ME, Jones V, Bodycombe NE, Soule CK, Gould J, Alexander B, Li A, Montgomery P, Wawer MJ, Kuru N, Kotz JD, Hon CS, Munoz B, Liefeld T, Dančík V, Bittker JA, Palmer M, Bradner JE, Shamji AF, Clemons PA, Schreiber SL. Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset. Cancer Discov. 2015 Nov;5(11):1210-23. doi: 10.1158/2159-8290.CD-15-0235. Epub 2015 Oct 19. PMID: 26482930; PMCID: PMC4631646. Rees MG, Seashore-Ludlow B, Cheah JH, Adams DJ, Price EV, Gill S, Javaid S, Coletti ME, Jones VL, Bodycombe NE, Soule CK, Alexander B, Li A, Montgomery P, Kotz JD, Hon CS, Munoz B, Liefeld T, Dančík V, Haber DA, Clish CB, Bittker JA, Palmer M, Wagner BK, Clemons PA, Shamji AF, Schreiber SL. Correlating chemical sensitivity and basal gene expression reveals mechanism of action. Nat Chem Biol. 2016 Feb;12(2):109-16. doi: 10.1038/nchembio.1986. Epub 2015 Dec 14. PMID: 26656090; PMCID: PMC4718762.
由ORCESTRA生成的CTRPv2药物数据集（PharmacoSet, PSet）。其元数据可在ORCESTRA平台获取，链接为：http://orcestra.ca/10.5281/zenodo.4429239 免责声明 CTRPv2数据集由布罗德研究所CTD²中心生成，最初通过《癌症治疗响应门户》（Cancer Therapeutics Response Portal, CTRP）发布。Haibe-Kains实验室对该数据集进行了重新处理与注释，以最大化其与其他药物基因组数据集的重叠度。 数据使用政策 CTD²按照其数据发布政策对外发布数据集。包括CTRPv2在内的DepMap数据集采用知识共享署名4.0（Creative Commons Attribution 4.0）许可协议进行分发。如需了解更多信息，请联系depmap@broadinstitute.org。 使用本数据集时，请引用以下文献： Seashore-Ludlow B, Rees MG, Cheah JH, Cokol M, Price EV, Coletti ME, Jones V, Bodycombe NE, Soule CK, Gould J, Alexander B, Li A, Montgomery P, Wawer MJ, Kuru N, Kotz JD, Hon CS, Munoz B, Liefeld T, Dančík V, Bittker JA, Palmer M, Bradner JE, Shamji AF, Clemons PA, Schreiber SL. 大规模小分子敏感性数据集的连接性挖掘. 癌症发现. 2015年11月;5(11):1210-23. doi: 10.1158/2159-8290.CD-15-0235. Epub 2015 Oct 19. PMID: 26482930; PMCID: PMC4631646. Rees MG, Seashore-Ludlow B, Cheah JH, Adams DJ, Price EV, Gill S, Javaid S, Coletti ME, Jones VL, Bodycombe NE, Soule CK, Alexander B, Li A, Montgomery P, Kotz JD, Hon CS, Munoz B, Liefeld T, Dančík V, Haber DA, Clish CB, Bittker JA, Palmer M, Wagner BK, Clemons PA, Shamji AF, Schreiber SL. 化学敏感性与基础基因表达的相关性分析揭示作用机制. 自然·化学生物学. 2016年2月;12(2):109-16. doi: 10.1038/nchembio.1986. Epub 2015 Dec 14. PMID: 26656090; PMCID: PMC4718762.
