Fusarium cerealis isolate:F-23-4.4 Genome sequencing

Fusarium cerealis is a toxin-producing plant pathogen that can infect a variety of economically important cereal crops, including corn, wheat, and oats. Among the toxic secondary metabolites produced by F. cerealis, nivalenol (NIV) is a mycotoxin that poses risks to both plant health and food safety. Genomes of plant-pathogenic fungi are replete with an array of virulence genes that encode various secondary metabolites, which play critical roles in the incidence and severity of diseases. The goal of this project is to present the first comprehensive high-quality genome assembly of F. cerealis, achieved through the utilization of long-read sequencing. This newly generated draft genome represents a vital resource that will facilitate future research endeavors aimed at exploring the genomic characteristics of pathogenic F. cerealis species prevalent in the Midwest, with a focus on identifying novel secondary metabolites that may contribute to their virulence and adaptability in diverse agricultural environments.

禾谷镰孢（Fusarium cerealis）是一种产毒植物病原菌，可侵染玉米、小麦、燕麦等多种具有重要经济价值的谷类作物。在该菌产生的有毒次生代谢产物中，雪腐镰孢醇（nivalenol, NIV）是一种真菌毒素，对植物健康与食品安全均构成威胁。植物病原真菌的基因组中富含大量编码各类次生代谢物的致病基因，这些基因在病害的发生与严重程度中发挥关键作用。本研究旨在公布首个全面且高质量的禾谷镰孢基因组组装结果，该组装通过长读长测序技术完成。此次新构建的草图基因组是一项重要的研究资源，将助力未来针对美国中西部地区流行的致病性禾谷镰孢菌株的基因组特征研究，重点聚焦于鉴定可能与其在多样农业环境中的致病力与适应性相关的新型次生代谢物。