miRNA sequencing from exosomes derived from M1-or M2-polarized bone-marrow derived macrophages (BMDMs).. miRNA sequencing from exosomes derived from M1-or M2-polarized bone-marrow derived macrophages (BMDMs).

We reported exosome-guided phenotype switches between M1- and M2-polarized BMDMs. M1- or M2-polarized BMDMs were successfully reprogrammed to M2- or M1-phenotype via the treatment of exosomes obtained from M2- or M1-polarized BMDMs. In this uploaded information, the exosomes from M1- and M2-polarized BMDMs were analyzed by high-throughput sequencing. Overall design: Examination of 2 different exosomes derived from M1- and M2-polarized BMDMs.

本研究报道了外泌体（exosome）介导的M1型与M2型极化骨髓源性巨噬细胞（Bone Marrow Derived Macrophages, BMDMs）之间的表型转换。经M2型或M1型极化BMDMs来源的外泌体处理后，M1型或M2型极化BMDMs可成功重编程为M2型或M1型表型。在本次上传的数据集信息中，研究人员对M1型和M2型极化BMDMs来源的外泌体进行了高通量测序分析。整体实验设计：对来源于M1型和M2型极化BMDMs的2种不同外泌体进行检测。