Hepatic gene expression in growth restricted fetal sheep after an acute hyperinsulinemic clamp or saline infusion at 0.9 gestation. Hepatic gene expression in growth restricted fetal sheep after an acute hyperinsulinemic clamp or saline infusion at 0.9 gestation

Here we used gene expresion microarray studies to test the global effect of IUGR on the fetal liver Overall design: Liver tissue was collected from normal (Control) and intrauterine growth restricted (IUGR) fetal sheep after a hyperinsulinemic-euglycemic clamp (INSULIN) or saline infusion (SALINE) at 0.9 gestation.

本研究采用基因表达微阵列（gene expression microarray）实验，探究宫内生长受限（intrauterine growth restriction, IUGR）对胎羊肝脏的全局影响。
实验设计：于妊娠0.9孕周时，对正常对照（Control）及宫内生长受限胎羊分别实施高胰岛素-正糖钳夹（INSULIN）或生理盐水输注（SALINE）处理，随后采集其肝脏组织。