In vivo pharmacodynamics of bicyclic 4-nitroimidazole analogs studied in mice.
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The mean log lung CFU’s in five independent invivo efficacy studies ranged between 6.07 and 6.66 in untreated infected mice.nd = not determined.ΔMean log lung CFU reduction compared to untreated controls. Each data represents mean value ± SEM from 5 animals.$Mean value from three independent experiments (n = 15).*Significant difference at PnsNo significant difference at P
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2015-12-02
