Nuclease Activity via Self-Activation and Anticancer Activity of a Mononuclear Copper(II) Complex: Novel Role of the Tertiary Butyl Group in the Ligand Frame
收藏Figshare2016-02-21 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Nuclease_Activity_via_Self_Activation_and_Anticancer_Activity_of_a_Mononuclear_Copper_II_Complex_Novel_Role_of_the_Tertiary_Butyl_Group_in_the_Ligand_Frame/2538931
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The copper complex [Cu(tBuPhimp)(Cl)] (1) derived from tridentate ligand tBuPhimpH having N2O donors was synthesized, and its molecular structure was determined. A phenoxyl radical complex was generated in solution at room temperature using Ce(IV). The nuclease and anticancer activities of 1 were investigated. The roles of the tert-butyl group and singlet oxygen in the DNA cleavage activity were also discussed.
创建时间:
2016-02-21



