Legionella oakridgensis ATCC 33761 = DSM 21215 Genome sequencing. Legionella oakridgensis ATCC 33761 = DSM 21215

L. oakridgensis was choosen for comparative analysis, since L. oakridgensis is far less pathogenic than L. pneumophila, but is still able to infect humans. Unlike all other Legionella species, L. oakridgensis is able to grow in media without additional cysteine and is, in contrast to the L. pneumophila strains, non-flagellated. For comparative analysis, we sequenced the genome of L. oakridgensis type strain ATCC 33761 and the nearly complete genome sequence of L. oakridgensis RV-2-2007 (cooling tower isolate, England).

选择橡树岭军团菌（Legionella oakridgensis）进行比较分析，原因在于其致病力显著弱于嗜肺军团菌（Legionella pneumophila），但仍可感染人类。与所有其他军团菌属（Legionella）物种不同，橡树岭军团菌可在无需额外添加半胱氨酸（cysteine）的培养基中生长；且与嗜肺军团菌菌株不同，该菌不具备鞭毛。为开展本次比较分析，我们对橡树岭军团菌模式菌株（type strain）ATCC 33761的基因组以及橡树岭军团菌RV-2-2007（分离自英国冷却塔的菌株）的近乎完整基因组序列进行了测序。