Diffuse astrocytoma, IDH-mutant - Male, 20 - Tissue image [5270730023435831]

This is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 20Clinical description: Brain tumor.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: GLIOMASDiagnosis: Diffuse astrocytoma, IDH-mutantResult of the histopathological examination: Diffuse astrocytoma IDH-1 mutant (G4 WHO2021)
IHC: IDH1R132+, p53 - mutant, ATRX+, Ki67 50%.Sample:Material: FFPECollecting method: Surgical specimenTopography: EYE, BRAIN AND OTHER PARTS OF CENTRAL NERVOUS SYSTEMOrgan: BRAINTissue: Temporal lobeType of staining: positive/IHCStaining: Not applicableAntibody: CD 45 (LCA)Technology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk

本数据集为格但斯克医科大学（Medical University Gdańsk）获取并存档于ZMDL-GUMED的脑组织样本组织病理学图像。该样本图像采用Pannoramic 250 3DHistech玻片扫描仪采集（放大倍率20倍），并以数字成像与通信（Digital Imaging and Communications in Medicine，DICOM）格式存储。

患者、样本及诊断的详细信息如下：
【患者信息】年龄20岁，临床表征为脑肿瘤，男性。诊断分类依据国际疾病分类-肿瘤学第3版（International Classification of Diseases for Oncology, 3rd Edition, ICD-O_3.2），分类编码为神经胶质瘤（GLIOMAS），具体诊断为弥漫性星形细胞瘤，IDH突变型。
组织病理学检查结果：IDH-1突变型弥漫性星形细胞瘤（世界卫生组织2021版分级G4）。
【免疫组化（Immunohistochemistry，IHC）结果】IDH1R132阳性，p53突变阴性，ATRX阳性，Ki67增殖指数为50%。

【样本信息】样本材质为福尔马林固定石蜡包埋（Formalin-Fixed Paraffin-Embedded，FFPE）组织；采集方式为手术标本；解剖部位为眼、脑及中枢神经系统其他部分；所属器官为脑；组织类型为颞叶；染色类型为免疫组化阳性；染色方法无适用方案；所用抗体为CD45（白细胞共同抗原，LCA）。

【成像技术与设备】使用Pannoramic 250 3DHistech设备，物镜倍率为20倍。本数据集来源机构为格但斯克医科大学（Medical University Gdańsk）。