Extensive literature search on glycoalkaloids and quinolizidine alkaloids - results of the selection for relevance and study characterisation

This report presents the outcome of extensive literature search on studies related to the chemistry and toxicity of glycoalkaloids and quinolizidine alkaloids in food and feed. The systematic literature search captures available scientific information published since 1950. 3,147 references were identified as potentially related to the chemistry and toxicity of glycoalkaloids in food and feed and 8,287 as potentially related to the chemistry and toxicity of quinolizidine alkaloids in food and feed. Upon screening of titles and abstracts of the candidates concerning glycoalkaloids, 1,645 were regarded as relevant, the number of included potentially relevant studies concerning quinolizidine alkaloids was 1,783. All included studies were characterised according to 10 different areas of interest of EFSA for further investigation.

Software needed to open the files: Microsoft Office - Excel; EndNote.

This upload supports the risk assessment on Quinolizidine alkaloids in food and feed: EFSA CONTAM Panel (EFSA Panel on Contaminants in the Food Chain), Schrenk D, Bodin L, Chipman JK, del Mazo J, Grasl-Kraupp B, Hogstrand C, Hoogenboom LR, Leblanc J-C, Nebbia CS, Nielsen E, Ntzani E, Petersen A, Sand S, Schwerdtle T, Vleminckx C, Wallace H, Alexander J, Cottrill B, Dusemund B, Mulder P, Arcella D, Baert K, Cascio C, Steinkellner H and Bignami M, 2019. Scientific opinion on the risks for animal and human health related to the presence of quinolizidine alkaloids in feed and food, in particular in lupins and lupin-derived products. EFSA Journal 2019;17(10):5860, 113 pp. 
https://doi.org/10.2903/j.efsa.2019.5860

本报告呈现了针对食品与饲料中糖生物碱（glycoalkaloids）和喹诺里西啶生物碱（quinolizidine alkaloids）的化学特性与毒性相关研究的系统性文献检索成果。本次系统性文献检索覆盖了1950年以来公开发表的全部可获取科学文献。其中，与食品和饲料中糖生物碱的化学特性及毒性相关的潜在关联文献共计3147篇，与食品和饲料中喹诺里西啶生物碱的化学特性及毒性相关的潜在关联文献共计8287篇。经对糖生物碱相关候选文献的标题与摘要进行筛查后，最终纳入1645篇相关研究；针对喹诺里西啶生物碱的潜在相关研究，最终纳入的有效文献数量为1783篇。所有纳入研究均依据欧洲食品安全局（EFSA）划定的10个重点研究领域完成特征标注，以供后续调研使用。

打开本数据集文件所需软件：Microsoft Office Excel、EndNote。

本上传数据集为食品和饲料中喹诺里西啶生物碱的风险评估提供支撑：欧洲食品安全局食品链污染物专家小组（EFSA CONTAM Panel）、Schrenk D、Bodin L、Chipman JK、del Mazo J、Grasl-Kraupp B、Hogstrand C、Hoogenboom LR、Leblanc J-C、Nebbia CS、Nielsen E、Ntzani E、Petersen A、Sand S、Schwerdtle T、Vleminckx C、Wallace H、Alexander J、Cottrill B、Dusemund B、Mulder P、Arcella D、Baert K、Cascio C、Steinkellner H及Bignami M，2019年。《关于饲料与食品中，特别是羽扇豆（lupins）及其衍生制品内喹诺里西啶生物碱残留对动物与人类健康构成的风险的科学意见》。《EFSA期刊》2019年；17(10):5860，共113页。https://doi.org/10.2903/j.efsa.2019.5860