Sustained liver HBsAg loss and clonal T and B cell expansion upon therapeutic DNA vaccination require low HBsAg levels

C57BL/6 mice samples transduced with AAV-HBV, followed by treatment with siRNA+TxTv, control siRNA+TxVx or control siRNA+empty plasmid. 10x genomics (VDJ) was performed in liver IHIC.
An rds object with the raw and normalised counts, the annotations is available.

本数据集以经腺相关病毒-乙型肝炎病毒（AAV-HBV）转导的C57BL/6小鼠样本为研究对象，随后分别予以siRNA+TxTv、对照siRNA+TxVx或对照siRNA+空质粒处理。在肝脏内免疫细胞（IHIC）中开展了10x基因组学（VDJ）测序。现已提供包含原始计数、归一化计数及注释信息的rds对象文件。