Additional file 1 of Host genetics and gut microbiota synergistically regulate feed utilization in egg-type chickens

Additional file 1: Table S1. Descriptive statistics for host phenotypes. Table S2. Summary statistics of whole-genome resequencing. Table S3. Summary statistics of 16S rRNA gene sequencing. Table S4. Detailed information on the SNPs associated with feed conversion ratio. Table S5. Detailed information on the SNPs associated with residual feed intake. Table S6. The SMR test based on the GWAS results for FCR. Table S7. The SMR test based on the GWAS results for RFI. Table S8. SRC analysis between the expression of each gene and FCR. Table S9. SRC analysis between the expression of each gene and RFI. Table S10. Differential expression genes detected between the top and bottom 20% FCR-ranked chickens. Table S11. Differential expression genes detected between the top and bottom 20% RFI-ranked chickens. Table S12. SRC analysis performed between the abundance of microbial taxa in each gut segment and FCR. Table S13. SRC analysis performed between the abundance of microbial taxa in each gut segment and RFI. Table S14. Wilcoxon rank-sum test on the relative abundance of each taxon between the top and bottom 20% FCR-ranked chickens. Table S15. Wilcoxon rank-sum test on the relative abundance of each taxon between the top and bottom 20% RFI-ranked chickens. Table S16. LEfSe analysis on the relative abundance of each taxon between the top and bottom 20% FCR/RFI-ranked chickens. Table S17. Heritabilityand cumulative abundance of heritable microbiota. Table S18. Detailed information on the significant SNPs associated with the abundance of key microbial genera. Table S19. The SMR test based on the mGWAS results for key microbial genera.

附加文件1：表S1为宿主表型描述性统计量；表S2为全基因组重测序汇总统计量；表S3为16S rRNA基因测序汇总统计量；表S4为与饲料转化率（Feed Conversion Ratio, FCR）相关的单核苷酸多态性（Single Nucleotide Polymorphism, SNP）详细信息；表S5为与剩余采食量（Residual Feed Intake, RFI）相关的单核苷酸多态性详细信息；表S6为基于饲料转化率全基因组关联分析（Genome-Wide Association Study, GWAS）结果的SMR检验；表S7为基于剩余采食量全基因组关联分析结果的SMR检验；表S8为各基因表达量与饲料转化率间的斯皮尔曼秩相关（Spearman Rank Correlation, SRC）分析；表S9为各基因表达量与剩余采食量间的斯皮尔曼秩相关分析；表S10为饲料转化率排名前20%与后20%的鸡只间检测到的差异表达基因；表S11为剩余采食量排名前20%与后20%的鸡只间检测到的差异表达基因；表S12为各肠道节段微生物类群丰度与饲料转化率间的斯皮尔曼秩相关分析；表S13为各肠道节段微生物类群丰度与剩余采食量间的斯皮尔曼秩相关分析；表S14为饲料转化率排名前20%与后20%的鸡只间各分类单元相对丰度的威尔科克森秩和检验；表S15为剩余采食量排名前20%与后20%的鸡只间各分类单元相对丰度的威尔科克森秩和检验；表S16为饲料转化率/剩余采食量排名前20%与后20%的鸡只间各分类单元相对丰度的线性判别分析效应大小（Linear Discriminant Analysis Effect Size, LEfSe）分析；表S17为可遗传微生物群的遗传力与累积丰度；表S18为与关键微生物属丰度相关的显著单核苷酸多态性详细信息；表S19为基于关键微生物属微生物全基因组关联分析（microbial Genome-Wide Association Study, mGWAS）结果的SMR检验。