Table 2_Prognostic value of the video head impulse test in sudden sensorineural hearing loss with vertigo: a systematic review and meta-analysis.docx

ObjectivesTo characterise the pattern of video head impulse test (vHIT) impairments in patients with sudden sensorineural hearing loss with vertigo (SSNHL-V), and to assess its correlation with audiological prognosis.
DesignWe systematically searched four databases (PubMed, Embase, Scopus, Cochrane Library) from inception to February 24, 2025, performed meta-analysis using Stata 18, and had the protocol prospectively registered with PROSPERO (CRD420251025900).
ResultsAmong patients with SSNHL-V, impairment of the posterior semicircular canal (PSCC) was found to be more common than that of the horizontal semicircular canal (HSCC) or anterior semicircular canal (ASCC). The pooled prevalence of PSCC abnormality was 50% (95% CI: 0.40–0.60; I2 = 87.65%, z = 14, p < 0.05). Regarding auditory prognosis, patients with reduced PSCC gain on vHIT had a 4.14-fold increased risk of poor hearing recovery (95% CI: 2.64–6.51; I2 = 7%, p = 0.36; z = 6.17, p < 0.05). Similarly, reduced HSCC gain was associated with a 3.06-fold increased risk (95% CI, 1.72–5.44; I2 = 0%, p = 0.96; z = 3.82, p < 0.05).
ConclusionIn patients with SSNHL-V, vHIT assessment revealed a higher rate of PSCC dysfunction compared to other semicircular canals, and impaired PSCC function serves as a significant predictor of auditory prognosis.

研究目的 明确伴眩晕的突发性感音神经性听力损失（sudden sensorineural hearing loss with vertigo, SSNHL-V）患者的视频头脉冲试验（video head impulse test, vHIT）损伤模式，并评估其与听力学预后的相关性。研究设计 系统检索自建库至2025年2月24日的4个数据库（PubMed、Embase、Scopus、Cochrane图书馆），采用Stata 18软件开展荟萃分析，研究方案已在PROSPERO平台完成前瞻性注册，注册号为CRD420251025900。研究结果 在伴眩晕的突发性感音神经性听力损失患者中，后半规管（posterior semicircular canal, PSCC）损伤的发生率高于水平半规管（horizontal semicircular canal, HSCC）与前半规管（anterior semicircular canal, ASCC）。后半规管异常的合并患病率为50%（95%置信区间：0.40~0.60；I²=87.65%，z=14，P<0.05）。在听力学预后方面，视频头脉冲试验中后半规管增益值降低的患者，其听力恢复不良的风险升高4.14倍（95%置信区间：2.64~6.51；I²=7%，P=0.36，z=6.17，P<0.05）。同样，水平半规管增益值降低与3.06倍的听力恢复不良风险升高相关（95%置信区间：1.72~5.44；I²=0%，P=0.96，z=3.82，P<0.05）。研究结论 伴眩晕的突发性感音神经性听力损失患者经视频头脉冲试验评估后，后半规管功能障碍的检出率高于其他半规管，且后半规管功能受损可作为听力学预后的重要预测因子。