Gene expression profile in response to SDH2 deletion during filament formation in both Spider medium and Spider medium supplemented with 100mM glucose

Transcriptional profiling of Candida albicans comparing SDH2 deletion mutant cells with the wild-type cells in both Spider medium and Spider medium supplemented with 100mM glucose The SDH2 deletion mutant sdh2Δ/Δ and the wild-type strain SC5314 were used to perform the microarray experiments. Two-condition experiments: sdh2Δ/Δ vs SC5314 in Spider midium and sdh2Δ/Δ vs SC5314 in Spider midium supplemented with 100mM glucose. Biological replicates: 3 SDH2 deletion mutant sdh2Δ/Δ samples (test group), 3 wild-type strain SC5314 samples (control group), independently grown and harvested. One replicate per array.

本数据集针对白色念珠菌（Candida albicans）开展转录谱分析，比较SDH2缺失突变体细胞与野生型细胞在Spider培养基（Spider medium）以及添加100mM葡萄糖的Spider培养基中的基因表达差异。实验采用SDH2纯合缺失突变体sdh2Δ/Δ与野生型菌株SC5314进行基因芯片实验，共设置两组对照实验：其一为Spider培养基中sdh2Δ/Δ与SC5314的比较，其二为添加100mM葡萄糖的Spider培养基中sdh2Δ/Δ与SC5314的比较。生物学重复设置为：实验组（SDH2缺失突变体sdh2Δ/Δ）与对照组（野生型菌株SC5314）各3份样本，所有样本均经独立培养并收获；每个芯片对应一个生物学重复样本。