Intranasal influenza vaccine mixed with adjuvant elicits protective antibodies against influenza viruses

To address challenges of limited vaccine effectiveness and needle-related hesitancy, this study evaluated intranasal delivery of Fluzone, a licensed split-inactivated influenza vaccine, with or without adjuvant.

为应对疫苗有效性不足以及与针头注射相关的接种犹豫两大挑战，本研究评估了获批上市的裂解灭活流感疫苗Fluzone经鼻给药的效果，分别设置含佐剂与不含佐剂两种给药方案。