Mantle cell lymphoma - Male, 64 - Tissue image [5020730020703161]

This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 64Clinical description: 5 cm palpable tumor in left axilla. Enlarged lymph node on ultrasound.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: MATURE B-CELL LYMPHOMASDiagnosis: Mantle cell lymphomaResult of the histopathological examination: Mantle cell lymphoma. Small to medium lymphoid cells. Irregular nuclear border. Inconspicuous nucleoli. Lymphoma cells: CD20+, Cyclin D1+, BCL-2+, BCL-6-, CD10-, CD3-, CD5-, CKAE1/AE3-, Ki-67 40%.Sample:Material: FFPECollecting method: Core-needle biopsyTopography: LYMPH NODESOrgan: LYMPH NODESTissue: Axillary lymph nodeType of staining: positive/IHCStaining: Not applicableAntibody: Cyclin D1Technology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk

本数据集为格但斯克医科大学（Medical University Gdańsk）获取并存档于ZMDL-GUMED的淋巴结组织样本的组织病理学图像。该样本图像采用Pannoramic 250 3DHistech切片扫描仪拍摄，放大倍数为20×，并以DICOM格式存储。

患者、样本及诊断详细信息如下：
患者：年龄64岁；临床特征：左侧腋窝可触及直径5cm的肿物，超声检查提示淋巴结肿大；性别：男性
诊断分类：依据ICD-O_3.2标准，分类编码为成熟B细胞淋巴瘤（MATURE B-CELL LYMPHOMAS）；最终诊断为套细胞淋巴瘤（Mantle cell lymphoma）
组织病理学检查结果：镜下符合套细胞淋巴瘤表现，肿瘤细胞为中小淋巴细胞，核边界不规则，核仁不明显；免疫表型检测结果：CD20阳性、Cyclin D1阳性、BCL-2阳性、BCL-6阴性、CD10阴性、CD3阴性、CD5阴性、CKAE1/AE3阴性，Ki-67增殖指数为40%。
样本信息：组织材质为福尔马林固定石蜡包埋（FFPE）；采集方式为核心针穿刺活检；解剖部位为淋巴结；受累器官为淋巴结；具体组织为腋窝淋巴结；染色类型为免疫组化（IHC）阳性；染色方案无特殊应用；所用抗体为Cyclin D1。
技术参数：扫描设备为Pannoramic 250 3DHistech，物镜放大倍数为20×；数据来源机构为格但斯克医科大学。