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RNA polymerase II elongation complex with Fapy-dG lesion with CMP added

NIAID Data Ecosystem2026-05-02 收录

RNA聚合酶转录机制

DNA损伤修复

数据链接：

https://www.rcsb.org/structure/8UKU 数据链接链接失效反馈

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RNA polymerase II elongation complex with Fapy-dG lesion with CMP added

结合有Fapy-dG损伤（Fapy-dG lesion）并添加了胞苷单磷酸（CMP）的RNA聚合酶II（RNA polymerase II）延伸复合物

应用场景：

创建时间：

2024-10-16

DNA损伤修复

抗癌药物设计

Homologous recombination repair (HRR), a crucial approach in DNA damage repair, is an attractive target in cancer therapy and drug design. The Bloom syndrome protein (BLM) is a 3′–5′ DNA helicase that

NIAID Data Ecosystem40

3-methyladenine dna-glycosylase from Archaeoglobus fulgidus

蛋白质结构解析

DNA损伤修复

3-methyladenine dna-glycosylase from Archaeoglobus fulgidus Descriptor: 3-METHYLADENINE DNA-GLYCOSYLASE, GLYCEROL, SODIUM ION Authors: Leiros, I, Nabong, M.P, Grosvik, K, Ringvoll, J, Haugland, G.T, U

Protein Data Bank Japan2023-12-13 更新20

DNA lesions can frequently precede DNA:RNA hybrid accumulation [RNA-seq]

DNA损伤修复

DNA:RNA杂交体

While DNA:RNA hybrids contribute to multiple genomic transactions, their unscheduled formation is a recognized source of DNA lesions. Here, through a suite of systematic screens, we rather observed th

NIAID Data Ecosystem10

Supplementary Table S2 from Hyper-Dependence on NHEJ Enables Synergy between DNA-PK Inhibitors and Low-Dose Doxorubicin in Leiomyosarcoma

肿瘤基因组学

DNA损伤修复

Supplementary Table S2: Sig3 scores and FGA values in LMS tumor samples. Sig3+ samples are predicted with a classifier trained in WGS LMS data. FGA values are calculated on CNVkit-based copy number pr

Figshare2023-12-15 更新30

p38-MK2 regulate RNA metabolism after UV light-induced DNA damage

DNA损伤修复

转录调控

Ultraviolet (UV) light induces the formation of bulky UV photoproducts in the genome that interfere with DNA replication and transcription. It is well-established how human cells repair UV light-induc

NIAID Data Ecosystem20

RNA polymerase II elongation complex with Fapy-dG lesion with CMP added

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