LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways [5_smRNA_A]. LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways [5_smRNA_A]

We analyzed small RNA expression changes in embryonic stem cells. Overall design: smallRNA expression profiling by high throughput sequencing in LIS1 Floxed/-, WT and OE mouse embryonic stem cells.

本研究分析了胚胎干细胞内小分子RNA(small RNA)的表达变化。实验设计概况：通过高通量测序(high throughput sequencing)对LIS1 Floxed/-、野生型(Wild Type, WT)及过表达(Overexpression, OE)小鼠胚胎干细胞开展小分子RNA表达谱分析。