Mutually exclusive events in 294 cell lines (GSK set).

In the potential space of double genomic events totaling 34191 co-events, we identified events that co-occurred less than expected by chance. These correspond to the extreme left tail of the distribution in Fig. 2. Events that co-occur less than expected by chance are mutually exclusive (observed freq = 0; BOLD), or partially exclusive (observed freq>0). Events with the most significant P-values AND maximal differences are reported here. Italics indicate P-values [0.06–0.10].在总计包含34191个共现事件的双基因组事件潜在空间中，我们筛选出了共现频率低于随机预期的事件。此类事件对应图2中分布的极端左尾区域。共现频率低于随机预期的事件可分为两类：完全互斥（观测频率=0，标注为BOLD）与部分互斥（观测频率>0）。本文报道了兼具最显著P值与最大差异幅度的事件。斜体标注的P值范围为0.06至0.10。