"Skeletal Fluorosis in Patients with Dental Fluorosis due to Groundwater Consumption in the Inhabitants of the Azua Compostela Province, Dominican Republic Period February-March of 2022”

Since 1888, a condition that manifests itself when fluoride is ingested in high amounts and for long periods of time, called fluorosis, has been analyzed, recorded and studied. In that order, when said effects of fluoride affect the teeth, it is usually called dental fluorosis or when it occurs particularly in the bones and joints, it is called skeletal fluorosis. Both effects of fluoride have been the subject of research to date, countries such as Mexico, Pakistan, India, the United States, and Argentina have significant data that serve as a reference for the identification of risk factors and future prevention.

自1888年起，针对长期大量摄入氟化物所引发的病症——氟中毒（fluorosis）——的分析、记录与研究工作便已启动。按受累部位划分，若氟化物的上述致病影响累及牙齿，通常称为牙型氟中毒（dental fluorosis）；若主要累及骨骼与关节，则称为骨型氟中毒（skeletal fluorosis）。迄今为止，这两类氟中毒均为相关研究的重点方向；墨西哥、巴基斯坦、印度、美国及阿根廷等国已积累了可用于风险因子识别与后续防控的大量参考数据。