Proteomics Data for "Cannabinoid Receptor 1 Antagonist Genistein Attenuates Marijuana-Induced Vascular Inflammation"

Supporting Olink (human) and Luminex (mouse) proteomics data for the study "Cannabinoid Receptor 1 Antagonist Genistein Attenuates Marijuana Induced Vascular Inflammation". Two data sets are included. First, circulating markers of inflammation are investigated using Olink proteomics analysis of human plasma collected from recreational smokers. After smoking a marijuana cigarette, plasma samples were serially drawn over 180 minutes to compared inflammation marker profiles. In the second data set, mouse plasma cytokines were quantified in EDTA anticoagulated plasma using a Luminex Analytes quantified using the Luminex mouse 48-plex assay (Procarta) from C57BL/6J mice treated with vehicle control, THC, or THC plus genistein.

本数据集为研究《大麻素受体1拮抗剂染料木黄酮（Genistein）减轻大麻诱导的血管炎症》提供支持性的Olink（人源）蛋白质组学与Luminex（小鼠源）蛋白质组学数据，共包含两个子数据集。第一个子数据集：针对休闲大麻使用者采集的人体血浆开展Olink蛋白质组学分析，以探究循环炎症标志物。受试者吸食大麻卷烟后，研究人员在180分钟内连续采集血浆样本，以对比不同时间点的炎症标志物表达谱。第二个子数据集：对经溶剂对照、四氢大麻酚（THC）或四氢大麻酚联合染料木黄酮处理的C57BL/6J小鼠，采用Luminex小鼠48重检测试剂盒（Procarta）对乙二胺四乙酸（EDTA）抗凝血浆中的小鼠血浆细胞因子进行定量检测。